The fruits (rose hips) of the Nootka rose are very high in vitamin C, and can be used to make tea, jelly, or syrup. In the past, rose hips were often used as a treatment for scurvy due to their high vitamin content. Some First Nations communities would eat the hips and new shoots, and also used teas made from the roots, leaves, or hips as treatments for various illnesses.
Patches of Nootka rose provide shelter and food for small birds and mammals. The hips are eaten by birds, insects, and small mammals, and deer will eat the leaves and young shoots. Nootka rose flowers also provide food for pollinator species, and several butterfly species lay their eggs on its leaves.